Private Project

AMR - Dying to Change the World

‘AMR – Dying to Change the World’ thrusts viewers into the heart of a looming catastrophe: Antimicrobial Resistance (AMR), the silent threat poised to shatter the foundations of global health, food systems, the environment and economic stability as we know it. This is not just a medical issue—this is an existential crisis. The World Health Organization warns that AMR, the insidious rise of drug-resistant superbugs, now stands shoulder-to-shoulder with the most terrifying dangers facing humanity, threatening to drag us back into a pre-antibiotic era where even minor infections could prove deadly.

The film unflinchingly exposes the root causes, devastating impact and the urgent, radical measures needed to stop AMR’s relentless advance—before we stumble into a new global pandemic, one far worse than Covid-19. This is the warning siren no leader can afford to ignore; action delayed today could mean millions of lives lost tomorrow.

What makes this story unforgettable is the chilling narrative device: we witness the unfolding horror through the eyes of AMR itself, given voice by the legendary Brian Cox (Succession). AMR breaks the fourth wall, speaking directly to us in a manner both intimate and unsettling, before taking on a godlike drone’s-eye view, reveling in its own evolution and unrestrained journey across the globe. It then confronts those on the front lines—scientists, doctors, and innovators—fighting desperately to slow its onslaught. The film’s climax is nothing short of haunting: AMR gazes into the camera, daring us to imagine a world in 2050 where medicine has failed, and our greatest enemy is one we created ourselves.

  • Alex Tweddle
    Director
  • Alex Tweddle
    Writer
  • Sally Davies
    Writer
  • Amit Khurana
    Writer
  • Yusuf Hamied
    Producer
  • Brian Cox
    Key Cast
    "AMR"
    Succession, Manhunter, Braveheart, Troy, The Bourne Films, X-Men United
  • Sharon Howard-Field
    Casting Director
  • James Buck
    Director of Photography - Locations
  • David Molina Perez
    Director of Photography - Studio
  • James Edward Barker
    Composer
  • Milford Killian-Dawson
    Aerial Director of Photography and Drone Pilot
  • Michael Powell
    Sound Designer and Mixer
  • Nick McCahearty
    Film Editor and Post-Production Supervisor
  • Jamie Dickinson
    Colourist and Offline editor
  • Alex Vanover
    Drone Pilot
  • Nick Walker
    Sound Recordist
  • Nathan Wiley
    Associate Producer
  • Matthew Mulligan
    Production Manager
  • Simon Bowen
    Script editor
  • Project Type:
    Documentary, Feature
  • Runtime:
    1 hour 8 minutes 15 seconds
  • Completion Date:
    June 30, 2025
  • Production Budget:
    250,000 GBP
  • Country of Origin:
    United Kingdom
  • Country of Filming:
    Denmark, France, Germany, India, United Kingdom
  • Language:
    English
  • Shooting Format:
    Digital 4K
  • Aspect Ratio:
    2.39
  • Film Color:
    Black & White and Color
  • First-time Filmmaker:
    No
  • Student Project:
    No
  • Digital Cinema Package:
    Unavailable
  • Cambridge Film Festival (CFF)
    Cambridge
    United Kingdom
    October 30, 2025
    World Premiere
    Audience Award
Director Biography - Alex Tweddle

A graduate of the prestigious Birmingham School of Speech Training and Dramatic Art and The London Film School, Alex is not only HEAT certified to operate in hostile environments but has also braved the world’s most perilous cities to capture stories that truly matter. With a flair for adventure and a passion for storytelling, Alex has spent over 30 years at the forefront of filmmaking, creating what industry insiders hail as electrifying, ground-breaking, and top-tier films that consistently redefine the cinematic landscape.

Renowned for his bold, edgy, and unmistakable style, Alex is celebrated for pushing creative boundaries and fearlessly tackling thought-provoking subjects. His films don’t just entertain—they challenge perceptions, provoke dialogue, and offer fresh perspectives on life, society, and the human condition.

Having competed at more than 150 film festivals worldwide and clinched over 50 prestigious awards—including Best Film, Message, Director, Sound, Music and Editing—Alex’s work resonates across borders. He has collaborated with some of the most talented actors and technicians in the business, making every project a masterclass in cinematic excellence.

Add Director Biography
Director Statement

“This film has relevance far beyond its subject matter. In fact, its relevance draws comparisons to the recent Covid-19 pandemic, having much to say about how political ambition, business ethics, and the media often hinder scientific progress in a game of Russian roulette with the lives of the most vulnerable. As a result of the film, I hope that people will better understand how scientists and science is performed.

Many people will not realise that is a global issue and I want this film to change that, so it doesn’t turn into a death sentence for millions of vulnerable people around the world.

There is clear commercial potential in the project, due to its unique visual style and strong acting talent. But beyond that, the objective is to make the film a world-class documentary that is both unusually imaginative, provocative, and superior in its genre.

I aimed to make it a film that the public, broadcasters, NGOs, and governments will embrace and talk about because they find it moving, gripping and above all, life-changing.”